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Treg and LRP1/CD91 levels before and after treatment in vitiligo patients, vs healthy individuals, show higher levels in vitiligo patients, demonstrating that abnormalities in the immune response contribute to the pathogenesis of vitiligo.22 Cytokines and chemokines Cytokines, especially IFN-γ and TNF-α, play a crucial role in melanocyte loss and vitiligo progression

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